The global market for the treatment of alcoholic liver diseases is projected to increase in size, expanding from USD 1,795.57 million in 2022 to USD 3,235.79 million by 2033, registering a compound annual growth rate (CAGR) of 5.5% from 2023 to 2033.
Alcohol-related liver disease (ALD) is a condition that arises from the consumption of excessive alcohol, exceeding the liver’s capacity to process it, leading to organ damage. The liver, responsible for numerous vital functions, both processes essential substances for the body and eliminates harmful ones. When alcohol undergoes liver breakdown, it produces a toxin that harms liver cells. Several factors contribute to increased alcohol consumption, including rising disposable incomes and a growing urban population. Urbanization, improved access to alcohol, and extensive advertising have all played roles in increased alcohol consumption, propelling market growth during the forecast period. However, the market may face hindrances due to the potential side effects associated with medications.
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Furthermore, governments are actively involved in research and development efforts to advance novel therapies for liver diseases, creating lucrative growth opportunities in the market.
Definition of the Global Alcoholic Liver Diseases Treatment Market: Alcoholic Liver Disease encompasses a wide range of clinical and histological conditions, including simple steatosis, cirrhosis, acute alcoholic hepatitis (with or without cirrhosis), and hepatocellular carcinoma as a complication of cirrhosis. The pathogenesis of ALD involves ethanol-mediated liver injury, inflammatory immune responses, changes in intestinal permeability, and alterations in the microbiome. The use of corticosteroids to improve outcomes remains controversial and likely affects short-term survival. Emerging therapies based on pathophysiological mechanisms, such as IL22, anakinra, and others, are currently under investigation.
In the United States, more than 22,000 people succumb to Alcoholic Liver Disease (ALD) each year, with approximately 75% of these deaths occurring among men. Interestingly, women develop the disease with lower levels of alcohol exposure than men. Following an ALD diagnosis, the most crucial step is to abstain from alcohol. Complete abstinence is the only way to potentially repair existing damage or halt the progression of the disease. Individuals struggling to quit drinking may be dealing with alcohol use disorder (AUD) and should seek medical advice regarding treatment options. Seeking treatment promotes long-term abstinence and reduces the risk of severe withdrawal symptoms, such as hallucinations and seizures, for which medications may be prescribed.
Scope of the Global Alcoholic Liver Diseases Treatment Market
This study classifies the alcoholic liver diseases treatment market into various categories based on indications, treatments, and distribution channels, encompassing both regional and global perspectives.
By Indication Outlook (Sales, USD Billion, 2019-2033):
- Alcoholic Hepatitis
- Alcoholic Steatohepatitis (Fatty Liver)
- Alcoholic Liver Fibrosis
- Alcoholic Liver Cirrhosis
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By Treatment Outlook (Sales, USD Billion, 2019-2033):
- Pentoxifylline
- Glucocorticosteroids
- Prednisone
- Triamcinolone
- Prednisolone
- Betaine
- Other Treatments
By Distribution Channel Outlook (Sales, USD Billion, 2019-2033):
- Hospital Pharmacies
- Retail Pharmacies
- Online Pharmacies
By Region Outlook (Sales, USD Billion, 2019-2033):
- North America
- US
- Canada
- Mexico
- Europe
- Germany
- Italy
- France
- UK
- Spain
- Poland
- Russia
- The Netherlands
- Norway
- Czech Republic
- Rest of Europe
- Asia Pacific
- China
- Japan
- India
- South Korea
- Indonesia
- Malaysia
- Thailand
- Singapore
- Australia & New Zealand
- Rest of Asia Pacific
- South America
- Brazil
- Argentina
- Colombia
- Rest of South America
- The Middle East & Africa
- Saudi Arabia
- UAE
- South Africa
- Northern Africa
- Rest of MEA
Prominent Market Participants in the Global Alcoholic Liver Diseases Treatment Market
The alcoholic liver diseases treatment market is characterized by robust competition, and industry leaders adopt a fiercely competitive approach through strategies such as product launches, partnerships, acquisitions, agreements, and expansion efforts to fortify their market standings. Many sector players are dedicated to expanding their global operations and nurturing enduring alliances.
Some of the major key players in the global alcoholic liver diseases treatment market include:
- Hoffmann-La Roche AG
- GlaxoSmithKline plc.
- Pfizer Inc.
- Novartis AG
- Akorn Operating Company LLC
- Johnson & Johnson Services, Inc.
- Wellona Pharma
- Teva Pharmaceuticals USA, Inc.
- Tianjin Jinjin Pharmaceutical Co. Ltd
- AdvaCare Pharma